Durand was born in Thunder Bay, Ontario, the son of Reina (née Perreault) and Serge Durand. He is of Frenc
h Canadian descent. Durand graduated from St. Ignatius High School in Thunder Bay. Durand is well known as a versatile character actor and has played series regulars on shows such as James Cameron's Dark Angel as Joshua, Agent Jay Swopes in the American remake of Touching Evil, as well as guest roles on CSI, CSI: Miami, ER, Without a Trace, Dead Like Me and others. He also recurred on the television show Stargate SG-1 as "Lord Zipacna" (based on the Mayan mythological figure Zipacna) and on Lost during its fourth and sixth seasons, in which he played as the antagonist Martin Keamy for 12 episodes.
Durand's first big movie break came when he was cast in Mystery, Alaska. His film credits include the role of Booth in Walking Tall, sidekick Red in Wild Hogs, the psychotic neo-nazi Jeeves Tremor in Smokin' Aces, the title role in Otis E., Gabriel in Legion, Little John in Robin Hood, and the hired thug Tucker in the 2007 remake of 3:10 to Yuma with Russell Crowe and Christian Bale. Recent film successes include, I Am Number Four in which he played The Commander and the role of Ricky opposite Hugh Jackman in Real Steel.
In 2012, he co-starred in Edwin Boyd: Citizen Gangster and David Cronenberg's Cosmopolis, the latter filmopposite Robert Pattinson, Paul Giamatti, and Samantha Morton. He will appear in The Truth with Andy García and Forrest Whitaker, and took on video game character Barry Burton in the 5th installment of the Resident Evil movie franchise, Resident Evil: Retribution. Durand's combined box office numbers total over 2.5 billion dollars worldwide. In 2013, he appeared in the film The Mortal Instruments. He will co-star in Darren Aronofsky's Noah, Atom Egoyan's two newest film's "Queen of the Night" and "The Devil's Knot.
Durand married long-time girlfriend Sandra Cho on October 1, 2010.
- Durands Character was created for I Am Number Four and did not appear in the novel. However, the character share characteristics with of two high ranking Mogadorians who did appear in the Novels. the first being General Andrakkus Sutekh who was the Mogadorian who caught and killed Number Three. The commander was also protrayed as the leader of the Mogadorians, not unlike Setrákus Ra.